[4] Club América 3-2 Puebla [5] 2022-05-14 23:00
Estádio: Estadio Azteca Round: 3
Juiz: Julio Gerardo Garcia Armenta Home Manager: Fernando Ortiz Away Manager: Nicolas Larcamon
Head to Head
| México - Liga MX | 2022/05/12 02:05 | Puebla v Club América | D | 1-1 |
| México - Liga MX | 2022/01/08 03:00 | Puebla v Club América | D | 1-1 |
| México - Liga MX | 2021/08/08 00:00 | Club América v Puebla | W | 2-0 |
| México - Liga MX | 2021/02/07 01:00 | Club América v Puebla | W | 1-0 |
| México - Liga MX | 2020/09/09 02:00 | Puebla v Club América | W | 2-3 |
| México - Liga MX | 2020/02/05 02:30 | Puebla v Club América | W | 0-1 |
| México - Liga MX | 2019/10/27 00:00 | Club América v Puebla | W | 2-0 |
| México - Liga MX | 2019/03/10 01:00 | Club América v Puebla | W | 1-0 |
Home History
| México - Liga MX | 2022/05/12 02:05 | Puebla v Club América | D | 1-1 |
| México - Liga MX | 2022/05/01 02:00 | Club América v Cruz Azul | D | 0-0 |
| México - Liga MX | 2022/04/24 00:00 | Tigres UANL v Club América | W | 0-2 |
| México - Liga MX | 2022/04/21 02:00 | Club América v Club León | W | 2-0 |
| México - Liga MX | 2022/04/16 02:06 | Tijuana v Club América | W | 1-3 |
| México - Liga MX | 2022/04/10 02:00 | Club América v Juárez FC | W | 3-0 |
| México - Liga MX | 2022/04/03 01:00 | Necaxa v Club América | W | 0-1 |
| América - Amigáveis | 2022/03/24 01:02 | Club América v Tigres UANL | L | 1-2 |
Away History
| México - Liga MX | 2022/05/12 02:05 | Puebla v Club América | D | 1-1 |
| México - Liga MX | 2022/05/08 22:00 | Puebla v Mazatlán FC | W | 5-3 |
| México - Liga MX | 2022/04/30 02:05 | Mazatlán FC v Puebla | L | 2-1 |
| México - Liga MX | 2022/04/23 00:00 | Puebla v Necaxa | L | 0-1 |
| México - Liga MX | 2022/04/20 00:00 | Pachuca v Puebla | L | 1-0 |
| México - Liga MX | 2022/04/16 22:00 | Club León v Puebla | W | 0-1 |
| México - Liga MX | 2022/04/09 00:00 | Puebla v Pumas | D | 2-2 |
| México - Liga MX | 2022/04/03 17:00 | Toluca v Puebla | L | 2-1 |