[4] Peñarol 1-0 Club Atlético Progreso [15] 2021-08-14 22:00
Estádio: Estádio Campeão do Siglo Round: 14
Juiz: Leodan Frankin Gonzalez Cabrera Home Manager: Jose Mauricio Larriera Away Manager: Maximiliano Viera
Head to Head
| Uruguai - Clausura | 2021/03/25 19:00 | Club Atlético Progreso v Peñarol | W | 0-2 |
| Uruguai - Apertura | 2020/10/06 21:00 | Peñarol v Club Atlético Progreso | W | 2-1 |
| Uruguai - Clausura | 2019/11/27 20:00 | Club Atlético Progreso v Peñarol | D | 0-0 |
| Uruguai - Torneo Intermedio | 2019/07/20 18:00 | Club Atlético Progreso v Peñarol | D | 1-1 |
| Uruguai - Apertura | 2019/05/26 21:00 | Peñarol v Club Atlético Progreso | D | 2-2 |
| Uruguai - Clausura | 2018/10/27 21:30 | Peñarol v Club Atlético Progreso | W | 1-0 |
| Uruguai - Torneo Intermedio | 2018/05/12 18:30 | Club Atlético Progreso v Peñarol | L | 4-3 |
| Uruguai - Apertura | 2018/04/29 18:30 | Club Atlético Progreso v Peñarol | W | 0-1 |
Home History
| Copa Sul-Americana | 2021/08/11 22:15 | Sporting Cristal v Peñarol | W | 1-3 |
| Uruguai - Apertura | 2021/08/06 21:00 | Cerro Largo FC v Peñarol | W | 0-1 |
| Uruguai - Apertura | 2021/08/01 21:00 | Peñarol v CA River Plate | W | 2-0 |
| Uruguai - Apertura | 2021/07/25 18:00 | Liverpool Montevideo v Peñarol | D | 3-3 |
| Copa Sul-Americana | 2021/07/23 00:30 | Peñarol v Nacional de Football | L | 0-1 |
| Copa Sul-Americana | 2021/07/16 00:30 | Nacional de Football v Peñarol | W | 1-2 |
| Uruguai - Apertura | 2021/07/11 23:30 | Peñarol v Cerrito | W | 2-0 |
| Uruguai - Apertura | 2021/07/04 19:00 | Nacional de Football v Peñarol | L | 2-0 |
Away History
| Uruguai - Apertura | 2021/08/06 18:00 | Club Atlético Progreso v Rentistas | D | 2-2 |
| Uruguai - Apertura | 2021/07/31 20:15 | Montevideo Wanderers v Club Atlético Progreso | L | 2-0 |
| Uruguai - Apertura | 2021/07/16 18:00 | Club Atlético Progreso v Boston River | W | 1-0 |
| Uruguai - Apertura | 2021/07/11 18:00 | Atletico Fenix Montevideo v Club Atlético Progreso | L | 2-1 |
| Uruguai - Apertura | 2021/07/05 18:00 | Club Atlético Progreso v Plaza Colonia | L | 1-2 |
| Uruguai - Apertura | 2021/06/29 18:00 | IA Sud America v Club Atlético Progreso | W | 2-4 |
| Uruguai - Apertura | 2021/06/24 16:00 | Deportivo Maldonado v Club Atlético Progreso | D | 1-1 |
| Uruguai - Apertura | 2021/06/19 15:15 | Club Atlético Progreso v Cerro Largo FC | D | 0-0 |