[1] Nacional de Football 2-0 Peñarol [6] 2021-07-04 19:00
Estádio: Estádio Gran Parque Central Round: 9
Juiz: Gustavo Tejera Home Manager: Alejandro Martin Capuccio Diaz Away Manager: Jose Mauricio Larriera
Head to Head
| Uruguai - Clausura | 2021/02/03 21:30 | Peñarol v Nacional de Football | D | 0-0 |
| Uruguai - Torneo Intermedio | 2020/12/13 20:30 | Peñarol v Nacional de Football | L | 3-2 |
| Uruguai - Apertura | 2020/08/09 18:00 | Nacional de Football v Peñarol | D | 1-1 |
| Uruguai - Grande Final | 2019/12/15 20:00 | Nacional de Football v Peñarol | W | 1-0 |
| Uruguai - Grande Final | 2019/12/11 23:30 | Peñarol v Nacional de Football | W | 0-2 |
| Uruguai - Clausura | 2019/11/17 19:00 | Nacional de Football v Peñarol | D | 0-0 |
| Uruguai - Torneo Intermedio | 2019/09/01 18:00 | Nacional de Football v Peñarol | W | 3-0 |
| Mundo - Amigáveis de Clubes | 2019/07/06 21:15 | Peñarol v Nacional de Football | L | 2-1 |
Home History
| Uruguai - Apertura | 2021/06/27 18:00 | Rentistas v Nacional de Football | D | 1-1 |
| Uruguai - Apertura | 2021/06/24 18:45 | Nacional de Football v Montevideo Wanderers | W | 3-0 |
| Uruguai - Apertura | 2021/06/19 18:00 | Boston River v Nacional de Football | D | 1-1 |
| Uruguai - Apertura | 2021/06/13 18:30 | Nacional de Football v Atletico Fenix Montevideo | W | 3-1 |
| Uruguai - Apertura | 2021/06/05 18:00 | Plaza Colonia v Nacional de Football | W | 1-2 |
| Uruguai - Apertura | 2021/06/02 23:30 | Nacional de Football v Cerro Largo FC | L | 1-2 |
| Uruguai - Apertura | 2021/05/30 23:30 | Nacional de Football v IA Sud America | W | 1-0 |
| Copa Libertadores | 2021/05/27 02:00 | Nacional de Football v Argentinos Jrs | W | 2-0 |
Away History
| Uruguai - Apertura | 2021/06/26 21:00 | Peñarol v Villa Espanola | D | 1-1 |
| Uruguai - Apertura | 2021/06/23 18:45 | Torque v Peñarol | W | 0-1 |
| Uruguai - Apertura | 2021/06/20 18:45 | Peñarol v Deportivo Maldonado | W | 4-0 |
| Uruguai - Apertura | 2021/06/12 23:15 | Peñarol v Rentistas | D | 1-1 |
| Uruguai - Apertura | 2021/06/06 23:15 | Montevideo Wanderers v Peñarol | D | 0-0 |
| Uruguai - Apertura | 2021/06/02 21:00 | Peñarol v Plaza Colonia | D | 0-0 |
| Uruguai - Apertura | 2021/05/30 21:00 | Peñarol v Boston River | W | 5-2 |
| Copa Sul-Americana | 2021/05/27 00:30 | Sport Huancayo v Peñarol | D | 0-0 |