[4] Peñarol 2-0 CA River Plate [6] 2021-03-06 23:15
Estádio: Estádio Campeão do Siglo Round: 11
Juiz: Andres Cunha Home Manager: Jose Mauricio Larriera Away Manager: Jorge Fossati
Head to Head
| Uruguai - Torneo Intermedio | 2020/10/17 21:00 | Peñarol v CA River Plate | L | 1-2 |
| Uruguai - Apertura | 2020/09/09 18:15 | CA River Plate v Peñarol | D | 0-0 |
| Uruguai - Clausura | 2019/11/09 22:00 | Peñarol v CA River Plate | W | 1-0 |
| Uruguai - Torneo Intermedio | 2019/08/24 18:00 | CA River Plate v Peñarol | L | 1-0 |
| Uruguai - Apertura | 2019/05/04 18:00 | CA River Plate v Peñarol | W | 0-2 |
| Uruguai - Clausura | 2018/07/29 18:00 | CA River Plate v Peñarol | W | 0-1 |
| Uruguai - Torneo Intermedio | 2018/05/20 22:00 | Peñarol v CA River Plate | W | 6-0 |
| Uruguai - Apertura | 2018/02/11 22:30 | Peñarol v CA River Plate | W | 4-1 |
Home History
| Uruguai - Clausura | 2021/02/26 20:00 | Liverpool Montevideo v Peñarol | D | 1-1 |
| Uruguai - Clausura | 2021/02/21 00:45 | Montevideo Wanderers v Peñarol | W | 0-1 |
| Uruguai - Clausura | 2021/02/17 22:30 | Cerro Largo FC v Peñarol | D | 1-1 |
| Uruguai - Clausura | 2021/02/14 20:00 | Rentistas v Peñarol | W | 0-1 |
| Uruguai - Clausura | 2021/02/11 23:00 | Peñarol v Deportivo Maldonado | D | 1-1 |
| Uruguai - Clausura | 2021/02/07 00:45 | Boston River v Peñarol | W | 1-2 |
| Uruguai - Clausura | 2021/02/03 21:30 | Peñarol v Nacional de Football | D | 0-0 |
| Uruguai - Clausura | 2021/01/31 20:00 | Danubio v Peñarol | W | 0-1 |
Away History
| Uruguai - Clausura | 2021/02/27 20:00 | CA River Plate v Montevideo Wanderers | D | 1-1 |
| Uruguai - Clausura | 2021/02/20 20:00 | CA River Plate v Cerro Largo FC | W | 2-0 |
| Uruguai - Clausura | 2021/02/17 13:00 | CA River Plate v Rentistas | D | 1-1 |
| Uruguai - Clausura | 2021/02/14 22:15 | Deportivo Maldonado v CA River Plate | W | 1-2 |
| Uruguai - Clausura | 2021/02/11 20:00 | CA River Plate v Boston River | W | 3-1 |
| Uruguai - Clausura | 2021/02/08 00:45 | Nacional de Football v CA River Plate | L | 3-0 |
| Uruguai - Clausura | 2021/02/04 13:00 | CA River Plate v Danubio | L | 0-4 |
| Uruguai - Clausura | 2021/02/01 00:30 | Defensor Sporting v CA River Plate | W | 0-2 |